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[gse39445] Effect of sleep restriction on the human transcriptome during exte...
Number of resources: 427 (427 raw, 0 normalizations, 0 DE files)In a cross balanced design human subjects were given one week of sufficient sleep and insufficient sleep (6 h per day). Following each of these conditions they were then kept... -
[gse45642] Circadian patterns of gene expression in the human brain and disru...
Number of resources: 670 (670 raw, 0 normalizations, 0 DE files)A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the... -
[gse98564] Gene expression biomarkers for neurobehavioral impairment from tot...
Number of resources: 199 (199 raw, 0 normalizations, 0 DE files)Healthy human adults were recruited to a sleep lab at Washington State University and remained there 7 consecutive days. Six received a well-rested Control condition of 10 h... -
[gse97554] Primate fetal hepatic response to maternal obesity: epigenetic sig...
Number of resources: 11 (11 raw, 0 normalizations, 0 DE files)The liver is a major site for synthesis, storage and redistribution of carbohydrates, proteins and lipids. In addition, it is well-known that maternal obesity (MO) increases... -
[gse43685] Early growth response protein-1 coordinates lipotoxicity-associate...
Number of resources: 8 (8 raw, 0 normalizations, 0 DE files)Maternal obesity during pregnancy leads to a pro-inflammatory milieu in the placenta. We conducted a global transcriptomic profiling in BeWo cells following palmitic acid (PA,... -
[gse127711] Blood Biomarkers for Memory: Towards Early Detection of Risk for ...
Number of resources: 734 (734 raw, 0 normalizations, 0 DE files)Short-memory dysfunction is a key early feature of Alzheimer Disease. Psychiatric patients may be at higher risk for memory dysfunction and subsequent Alzheimer due to the... -
[gse89594] Integrated network analysis reveals genotype-phenotype correlation...
Number of resources: 94 (94 raw, 0 normalizations, 0 DE files)Williams Syndrome (WS) is a rare neurodevelopmental disorder caused by heterozygous deletions in a chromosome 7q11.23 region typically encompassing 26-28 genes. WS patients... -
[gse119995] Exposure-induced changes of plasma mRNA expression levels in pati...
Number of resources: 72 (72 raw, 0 normalizations, 0 DE files)Anxiety disorders including panic disorders with or without agoraphobia are the most prevalent mental disorders. Exposure is a core technique within the framework of cognitive... -
[gse94119] Gene expression and response to psychological therapy
Number of resources: 315 (315 raw, 0 normalizations, 0 DE files)This study represents the first investigation of genome-wide expression profiles with respect to psychological treatment outcome. Participants (n=102) with panic disorder or... -
[gse18212] THE EFFECTS OF ALCOHOLISM ON THE HUMAN BASOLATERAL AMYGDALA
Number of resources: 2 (2 raw, 0 normalizations, 0 DE files)Alcohol affects gene expression in several brain regions. The amygdala is a key structure in the brain’s emotional system and in recent years the crucial importance of the... -
[gse60190] Genetic Neuropathology of Obsessive Psychiatric Syndromes
Number of resources: 133 (133 raw, 0 normalizations, 0 DE files)Anorexia nervosa (AN), bulimia nervosa (BN), and obsessive-compulsive disorder (OCD) are complex psychiatric disorders with shared obsessive features, thought to arise from the... -
[gse54400] Transcriptome analysis of human umbilical cord fibroblasts from ba...
Number of resources: 47 (47 raw, 0 normalizations, 0 DE files)In pregnancies involving preeclampsia (PE), there is evidence that the fetal-placental unit is under oxidative stress. Here we examined primary cell lines generated from... -
[gse27272] Comprehensive Study of Tobacco Smoke-Related Transcriptome Alterat...
Number of resources: 183 (183 raw, 0 normalizations, 0 DE files)Maternal smoking has a severe negative effect on all stages of pregnancy that in consequence impairs fetal growth and development. Tobacco smoke-related defects are well... -
[gse114852] Gene expression in cord blood links genetic risk for neurodevelop...
Number of resources: 149 (149 raw, 0 normalizations, 0 DE files)Prenatal exposure to maternal stress and depression has been identified as a risk factor for adverse behavioral and neurodevelopmental outcomes in early... -
[gse51108] Gene expression in liver tissue from Ghrh-KO and normal (wild-type...
Number of resources: 7 (6 raw, 1 normalizations, 0 DE files)The hypothalamus has recently emerged as a key regulator of metabolism and aging in mammals. We have examined the impact of targeted disruption of hypothalamic hypophysiotropic... -
[gse30032] Deregulation of Gene Expression induced by Environmental Tobacco S...
Number of resources: 104 (104 raw, 0 normalizations, 0 DE files)Passive smoke intake by pregnant women may have detrimental effects such as spontaneous abortion, lower birth weight, stillbirth, and reduced infant lung function. To extend our... -
[gse52790] lncRNA and mRNA expression data in peripheral blood sampled from M...
Number of resources: 22 (22 raw, 0 normalizations, 0 DE files)Long noncoding RNAs (lncRNAs) are pervasively transcribed and have a direct role in the regulation of genes involved in neural plasticity and cognitive function. Moreover,... -
[gse19738] Major Depressive Disorder blood gene expression
Number of resources: 132 (132 raw, 0 normalizations, 0 DE files)Background: Major Depressive Disorder (MDD) is a moderately heritable disorder with a high lifetime prevalence. At present, laboratory blood tests to support MDD diagnosis are... -
[gse98793] Gene expression analysis in whole blood samples obtained from dono...
Number of resources: 192 (192 raw, 0 normalizations, 0 DE files)This study investigated gene expression changes in whole blood samples obtained from donors diagnosed with major depressive disorder (MDD) compared to healthy controls.... -
[gse56931] Blood gene expression reveals reduced circadian rhythmicity in ind...
Number of resources: 249 (249 raw, 0 normalizations, 0 DE files)To address whether changes in gene expression in blood cells with sleep loss are different in individuals resistant and sensitive to sleep deprivation (SD).; Blood draws every...
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