-
[gse97154] MicroRNAs 146a/b-5p, 425-3p and 24-3p are markers of antidepressan...
Number of resources: 445 (445 raw, 0 normalizations, 0 DE files)Background: Antidepressants (ADs) are the most common treatment for major depressive disorder (MDD). However, only about 30% of patients experience adequate response after a... -
[gse144136] Single-nucleus RNA-seq in the post-mortem brain in major depressi...
Number of resources: 34 (34 raw, 0 normalizations, 0 DE files)We performed high-throughput snRNA-seq using the 10X Genomics Chromium platform on archived post-mortem dorsolateral prefrontal cortex (BA9) tissue in MDD subjects who died by... -
[gse39445] Effect of sleep restriction on the human transcriptome during exte...
Number of resources: 427 (427 raw, 0 normalizations, 0 DE files)In a cross balanced design human subjects were given one week of sufficient sleep and insufficient sleep (6 h per day). Following each of these conditions they were then kept... -
[gse45642] Circadian patterns of gene expression in the human brain and disru...
Number of resources: 670 (670 raw, 0 normalizations, 0 DE files)A cardinal symptom of Major Depressive Disorder (MDD) is the disruption of circadian patterns. Yet, to date, there is no direct evidence of circadian clock dysregulation in the... -
[gse98564] Gene expression biomarkers for neurobehavioral impairment from tot...
Number of resources: 199 (199 raw, 0 normalizations, 0 DE files)Healthy human adults were recruited to a sleep lab at Washington State University and remained there 7 consecutive days. Six received a well-rested Control condition of 10 h... -
[gse94729] Sexually dimorphic methylation of CD3+ T-lymphocyte DNA in offspri...
Number of resources: 76 (76 raw, 0 normalizations, 0 DE files)Maternal obesity impacts the health of offspring, increasing the risk of developing obesity and/or other metabolic dysregulation in childhood or later in life. Using a... -
[gse69769] MeDIP and hMeDIP assays using human placentas of obese and lean (h...
Number of resources: 4 (4 raw, 0 normalizations, 0 DE files)Maternal obesity has both a direct effect on the outcome of pregnancy but also programs the fetus for obesity and metabolic syndrome in later life. Due to its roles at the... -
[gse120062] DNA Methylation data from frozen placental tissue
Number of resources: 38 (38 raw, 0 normalizations, 0 DE files)Maternal obesity alters placental tissue function and morphology with a corresponding increase in local inflammation.; We and others showed that placenta size, inflammation and... -
[gse43685] Early growth response protein-1 coordinates lipotoxicity-associate...
Number of resources: 8 (8 raw, 0 normalizations, 0 DE files)Maternal obesity during pregnancy leads to a pro-inflammatory milieu in the placenta. We conducted a global transcriptomic profiling in BeWo cells following palmitic acid (PA,... -
[gse127711] Blood Biomarkers for Memory: Towards Early Detection of Risk for ...
Number of resources: 734 (734 raw, 0 normalizations, 0 DE files)Short-memory dysfunction is a key early feature of Alzheimer Disease. Psychiatric patients may be at higher risk for memory dysfunction and subsequent Alzheimer due to the... -
[gse89595] Signiture microRNA expression patterns identified in Williams synd...
Number of resources: 66 (66 raw, 0 normalizations, 0 DE files)Williams Syndrome (WS) is a rare neurodevelopmental disorder caused by heterozygous deletions in a chromosome 7q11.23 region typically encompassing 26-28 genes. WS patients... -
[gse87768] Circulating miRNA Associated with Posttraumatic Stress Disorder in...
Number of resources: 48 (48 raw, 0 normalizations, 0 DE files)Objective: Posttraumatic stress disorder (PTSD) affects a high proportion of returning combat veterans, but the biological mechanisms of PTSD remain unclear. Circulating micro... -
[gse71661] TTF1 and TKTL1 mRNAs in Extracellular Vesicles as a Blood Biomarke...
Number of resources: 57 (57 raw, 0 normalizations, 0 DE files)Lung cancer remains the greatest cause of cancer related deaths and Low Dosage Computerized Tomography (LDCT) has been shown to improve early detection of lung cancer and... -
[gse89594] Integrated network analysis reveals genotype-phenotype correlation...
Number of resources: 94 (94 raw, 0 normalizations, 0 DE files)Williams Syndrome (WS) is a rare neurodevelopmental disorder caused by heterozygous deletions in a chromosome 7q11.23 region typically encompassing 26-28 genes. WS patients... -
[gse109499] Gain-of-function mutations in the serotonin transporter cluster t...
Number of resources: 10 (10 raw, 0 normalizations, 0 DE files)The human serotonin transporter SERT catalyzes serotonin reuptake at the synapse to terminate neurotransmission, and is targeted by therapeutics treating depression and anxiety... -
[gse104376] HM450 analysis pregnancy anxiety
Number of resources: 45 (45 raw, 0 normalizations, 0 DE files)DNA methylation profiling of low versus high pregnancy anxiety (22 versus 23 cord blood samples, respectively) using the Illumina Infinium HM450 array -
[gse80261] DNA methylation signature of human fetal alcohol spectrum disorder
Number of resources: 216 (216 raw, 0 normalizations, 0 DE files)Prenatal alcohol exposure is the leading preventable cause of behavioural and cognitive deficits, which may affect between 2-5% of children in North America. While the... -
[gse78975] Longitudinal DNA Methylome analysis from saliva sample of adolesce...
Number of resources: 96 (96 raw, 0 normalizations, 0 DE files)A cohort of adolescents and young adults took part in this longitudinal 5-year follow-up study. We selected four groups of subjects from the same community sample carefully... -
[gse128840] Neuronal deletion of Gtf2i, associated with Williams syndrome, ca...
Number of resources: 6 (6 raw, 0 normalizations, 0 DE files)Williams syndrome (WS), caused by a heterozygous microdeletion in 7q11.23, is a neurodevelopmental disorder characterized by hypersociability and neurocognitive abnormalities.... -
[gse119995] Exposure-induced changes of plasma mRNA expression levels in pati...
Number of resources: 72 (72 raw, 0 normalizations, 0 DE files)Anxiety disorders including panic disorders with or without agoraphobia are the most prevalent mental disorders. Exposure is a core technique within the framework of cognitive...
